Originalpublikationer Per-Henrik Groop
Ahola A, Saraheimo M, Freese R, Mikkilä V, Mäkimattila S, Forsblom C, Groop P-H, on behalf of the FinnDiane Study Group. Ahola A, Saraheimo M, Freese R, Mikkilä V, Mäkimattila S, Forsblom C, Groop P-H, on behalf of the FinnDiane Study Group. Fear of hypoglycaemia and self-management in type 1 diabetes. J Clin Trans Endocrinol 4: 13-18, 2016
Ahola AJ, Freese R, Mäkimattila S, Forsblom C, Groop PH; FinnDiane Study Group. Dietary patterns are associated with various vascular health markers and complications in type 1 diabetes. J Diabetes Complications 30: 1144-50, 2016
Berglund LM, Lyssenko V, Ladenvall C, Kotova O, Edsfeldt A, Pilgaard K, Alkayyali S, Brøns C, Forsblom C, Jonsson A, Zetterqvist AV, Nitulescu M, McDavitt CR, Dunér P, Stancáková A, Kuusisto J, Ahlqvist E, Lajer M, Tarnow L, Madsbad S, Rossing P, Kieffer TJ, Melander O, Orho-Melander M, Nilsson P, Groop PH, Vaag A, Lindblad B, Gottsäter A, Laakso M, Goncalves I, Groop L, Gomez MF. Glucose-dependent insulinotropic polypeptide (GIP) stimulates osteopontin expression in the vasculature via endothelin-1 and CREB. Diabetes 65: 239-54, 2016
Chen W, Laiho S, Vaittinen O, Halonen L, Ortiz F, Forsblom C, Groop PH, Lehto M, Metsälä M. Biochemical pathways of breath ammonia (NH3) generation in patients with end-stage renal disease undergoing hemodialysis. J Breath Res 10: 036011, 2016
Chen W, Roslund K, Fogarty CL, Pussinen PJ, Halonen L, Groop PH, Metsälä M, Lehto M. Detection of hydrogen cyanide from oral anaerobes by cavity ring down spectroscopy. Sci Rep 6: 22577, 2016
Cherney D, Lund SS, Perkins BA, Groop PH, Cooper ME, Kaspers S, Pfarr E, Woerle HJ, von Eynatten M. The effect of sodium glucose cotransporter 2 inhibition with empagliflozin on microalbuminuria and macroalbuminuria in patients with type 2 diabetes. Diabetologia 59: 1860-1870, 2016
Esposito P, Mereu R, De Barbieri G, Rampino T, Di Toro A, Groop PH, Dal Canton A, Bernardi L. Trained breathing-induced oxygenation acutely reverses cardiovascular autonomic dysfunction in patients with type 2 diabetes and renal disease. Acta Diabetol 53: 217-226, 2016
Feodoroff M, Harjutsalo V, Forsblom C, Sandholm N, Groop PH; FinnDiane Study Group. The impact of smoking on the effect of the rs4972593 genetic variant on end-stage renal disease. Diabet Med 33: 1301-1303, 2016
Feodoroff M, Harjutsalo V, Forsblom C, Thorn L, Wadén J, Tolonen N, Lithovius R, Groop PH. Smoking and progression of diabetic nephropathy in patients with type 1 diabetes. Acta Diabetol 53: 525-533, 2016
Gordin D, Bernardi L, Rosengård-Bärlund M, Mäkinen VP, Soro-Paavonen A, Forsblom C, Sandelin A, Groop PH. Oxygen deteriorates arterial function in type 1 diabetes. Acta Diabetol 53: 349-357, 2016
Gordin D, Groop PH. Aspects of Hyperglycemia Contribution to Arterial Stiffness and Cardiovascular Complications in Patients With Type 1 Diabetes. J Diabetes Sci Technol 10: 1059-1064, 2016 (Review)
Gordin D, Saraheimo M, Tuomikangas J, Soro-Paavonen A, Forsblom C, Paavonen K, Steckel-Hamann B, Vandenhende F, Nicolaou L, Pavo I, Koivisto V, Groop PH. Influence of Postprandial Hyperglycemic Conditions on Arterial Stiffness in Patients With Type 2 Diabetes. J Clin Endocrinol Metab 101: 1134-1143, 2016
Harjutsalo V, Maric-Bilkan C, Forsblom C, Groop PH; FinnDiane Study Group. Age at menarche and the risk of diabetic microvascular complications in patients with type 1 diabetes. Diabetologia 59: 472-480, 2016
Lassenius MI, Ahola AJ, Harjutsalo V, Forsblom C, Groop PH, Lehto M. Endotoxins are associated with visceral fat mass in type 1 diabetes. Sci Rep 6: 38887, 2016
Ottosson-Laakso E, Tuomi T, Forsén B, Gullström M, Groop PH, Groop L, Vikman P. Influence of Familial Renal Glycosuria Due to Mutations in the SLC5A2 Gene on Changes in Glucose Tolerance over Time. PLoS One 11: e0146114, 2016
Pedigo CE, Ducasa GM, Leclercq F, Sloan A, Mitrofanova A, Hashmi T, Molina-David J, Ge M, Lassenius MI, Forsblom C, Lehto M, Groop PH, Kretzler M, Eddy S, Martini S, Reich H, Wahl P, Ghiggeri G, Faul C, Burke GW 3rd, Kretz O, Huber TB, Mendez AJ, Merscher S, Fornoni A. 13. Local TNF causes NFATc1-dependent cholesterol-mediated podocyte injury. J Clin Invest 126: 3336-3350, 2016
Perkovic V, Agarwal R, Fioretto P, Hemmelgarn BR, Levin A, Thomas MC, Wanner C, Kasiske BL, Wheeler DC, Groop PH; Conference Participants. Management of patients with diabetes and CKD: Report from a “Kidney Disease, Improving Global Outcomes” (KDIGO) Controversies Conference. Kidney Int 90: 1175-1183, 2016
Porta M, Toppila I, Sandholm N, Hosseini SM, Forsblom C, Hietala K, Borio L, Harjutsalo V, Klein BE, Klein R, Paterson AD; DCCT/EDIC Research Group., Groop PH; FinnDiane Study Group. Variation in SLC19A3 and protection from microvascular damage in type 1 diabetes. Diabetes 5: 1022-1030, 2016
Sanahuja J, Alonso N, Diez J, Ortega E, Rubinat E, Traveset A, Alcubierre N, Betriu À, Castelblanco E, Hernández M, Purroy F, Arcidiacono MV, Jurjo C, Fernández E, Puig-Domingo M, Groop PH, Mauricio D. Increased Burden of Cerebral Small Vessel Disease in Patients With Type 2 Diabetes and Retinopathy. Diabetes Care 39: 1614-1620, 2016
Sas KM, Kayampilly P, Byun J, Nair V, Hinder LM, Hur J, Zhang H, Lin C, Qi NR, Michailidis G, Groop PH, Nelson RG, Darshi M, Sharma K, Schelling JR, Sedor JR, Pop-Busui R, Weinberg JM, Soleimanpour SA, Abcouwer SF, Gardner TW, Burant CF, Feldman EL, Kretzler M, Brosius FC 3rd, Pennathur S. Tissue-specific metabolic reprogramming drives nutrient flux in diabetic complications. JCI Insight 1: e86976, 2016
Saurus P, Kuusela S, Dumont V, Lehtonen E, Fogarty CL, Lassenius MI, Forsblom C, Lehto M, Saleem MA, Groop PH, Lehtonen S. Cyclin-dependent kinase 2 protects podocytes from apoptosis. Sci Rep 6: 21664, 2016
Thomas MC, Paldánius PM, Ayyagari R, Ong SH, Groop PH. Systematic Literature Review of DPP-4 Inhibitors in Patients with Type 2 Diabetes Mellitus and Renal Impairment. Diabetes Ther 7: 439-454, 2016 (Review)
Zonszein J, Groop PH. Strategies for Diabetes Management: Using Newer Oral Combination Therapies Early in the Disease. Diabetes Ther 7: 621-639, 2016 (Review)
Originalpublikationer Tiinamaija Tuomi
Bacos K, Gillberg L, Volkov P, Olsson AH, Hansen T, Pedersen O, Gjesing AP, Eiberg H, Tuomi T, Almgren P, Groop L, Eliasson L, Vaag A, Dayeh T, Ling C. Blood-based biomarkers of age-associated epigenetic changes in human islets associate with insulin secretion and diabetes. Nat Commun 7: 11089, 2016
Dayeh T, Tuomi T, Almgren P, Perfilyev A, Jansson PA, de Mello VD, Pihlajamäki J, Vaag A, Groop L, Nilsson E, Ling C. DNA methylation of loci within ABCG1 and PHOSPHO1 in blood DNA is associated with future type 2 diabetes risk. Epigenetics 11: 482-488, 2016
Fuchsberger C, Flannick J, Teslovich TM, Mahajan A, Agarwala V, Gaulton KJ, Tuomi T et al. The genetic architecture of type 2 diabetes. Nature 536: 41-47, 2016
Ottosson-Laakso E, Tuomi T, Forsén B, Gullström M, Groop PH, Groop L, Vikman P. Influence of Familial Renal Glycosuria Due to Mutations in the SLC5A2 Gene on Changes in Glucose Tolerance over Time. PLoS One 11: e0146114, 2016
Prasad RB, Lessmark A, Almgren P, Kovacs G, Hansson O, Oskolkov N, Vitai M, Ladenvall C, Kovacs P, Fadista J, Lachmann M, Zhou Y, Sonestedt E, Poon W, Wollheim CB, Orho-Melander M, Stumvoll M, Tuomi T, Pääbo S, Koranyi L, Groop L. Excess maternal transmission of variants in the THADA gene to offspring with type 2 diabetes. Diabetologia 59: 1702-1713, 2016
Rasouli B, Andersson T, Carlsson PO, Grill V, Groop L, Martinell M, Storm P, Tuomi T, Carlsson S. Smoking and the Risk of LADA: Results From a Swedish Population-Based Case-Control Study. Diabetes Care 39: 794-800, 2016
Surendran P, Drenos F, Young R, Warren H, Cook JP, Manning AK, Tuomi T et al. Trans-ancestry meta-analyses identify rare and common variants associated with blood pressure and hypertension.
Nat Genet 48: 1151-1161, 2016
Tuomi T, Nagorny CL, Singh P, Bennet H, Yu Q, Alenkvist I, Isomaa B, Östman B, Söderström J, Pesonen AK, Martikainen S, Räikkönen K, Forsén T, Hakaste L, Almgren P, Storm P, Asplund O, Shcherbina L, Fex M, Fadista J, Tengholm A, Wierup N, Groop L, Mulder H. 11. Increased Melatonin Signaling Is a Risk Factor for Type 2 Diabetes. Cell Metab 23: 1067-1077, 2016
Övriga publikationer Tiinamaija Tuomi
Laakso M, Groop L, Isomaa B, Honkasalo M, Juselius P, Lindström J, Meinander T, Nuutinen H, Saltevo J, Syvänne M, Tuomi T. [Update on Current Care Guideline. Diabetes]. Duodecim 132: 881-882, 2016
Originalpublikationer Mikael Knip
Galli E, Härkönen T, Sainio MT, Ustav M, Toots U, Urtti A, Yliperttula M, Lindahl M, Knip M, Saarma M, Lindholm P. Increased circulating concentrations of mesencephalic astrocyte-derived neurotrophic factor in children with type 1 diabetes. Sci Rep 6: 29058, 2016
Helminen O, Pokka T, Tossavainen P, Ilonen J, Knip M, Veijola R. Continuous glucose monitoring and HbA1c in the evaluation of glucose metabolism in children at high risk for type 1 diabetes mellitus. Diabetes Res Clin Pract 120: 89-96, 2016
Ilonen J, Kiviniemi M, Lempainen J, Simell O, Toppari J, Veijola R, Knip M; Finnish Pediatric Diabetes Register. Genetic susceptibility to type 1 diabetes in childhood - estimation of HLA class II associated disease risk and class II effect in various phases of islet autoimmunity. Pediatr Diabetes 17: 8-16, 2016
Knip M, Siljander H, Ilonen J, Simell O, Veijola R. Role of humoral beta-cell autoimmunity in type 1 diabetes. Pediatr Diabetes 17:17-24, 2016
Seppälä E, Sillanpää S, Nurminen N, Huhtala H, Toppari J, Ilonen J, Veijola R, Knip M, Sipilä M, Laranne J, Oikarinen S, Hyöty H. Human enterovirus and rhinovirus infections are associated with otitis media in a prospective birth cohort study..J Clin Virol 85: 1-6, 2016
Simre K, Uibo O, Peet A, Tillmann V, Kool P, Hämäläinen AM, Härkönen T, Siljander H, Virtanen S, Ilonen J, Knip M, Uibo R; DIABIMMUNE Study Group.
Exploring the risk factors for differences in the cumulative incidence of coeliac disease in two neighboring countries: the prospective DIABIMMUNE study. Dig Liver Dis 48: 1296-1301, 2016
Yassour M, Vatanen T, Siljander H, Hämäläinen AM, Härkönen T, Ryhänen SJ, Franzosa EA, Vlamakis H, Huttenhower C, Gevers D, Lander ES, Knip M; DIABIMMUNE Study Group, Xavier RJ. Natural history of the infant gut microbiome and impact of antibiotic treatment on bacterial strain diversity and stability. Sci Transl Med 8: 343ra81, 2016